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Bolsas de Doutoramento

Fumarola, Furnas (ilha de S. Miguel) (Foto: Ricardo Camarinho)

Understanding the respiratory effects of volcanogenic air pollution: a toxicogenomic approach

Resumo


​Volcanogenic air pollution has been widely ignored as a potential source of pollutants. In the Azorean archipelago, the Furnas volcano is responsible for the emission of 1000 tonsperday of CO2, and volcanic activity is marked by active fumarolic fields, hot and cold CO2-rich springs and soil diffuse degassing phenomena. Several hazardous gases (some radioactive) are released along with particulate matter and heavy metals. Previous studies have revealed an association between chronic exposures to volcanogenic pollution and persistent respiratory inflammation, genotoxicity and carcinogenic incidences. However, the molecular/genetic mechanisms underlying these respiratory effects are not understood and early biomarkers of exposure and effect in humans inhabiting environments with volcanic activity are not available. The present project will employ a bioindicator species, Mus musculus, for identifying histological (histomorphometry, immunohistochemistry), cytogenetic (DNA damage) and genomic (gene expression profiling) changes that potentially contribute to volcanogenic related respiratory effects and identify gene markers for human biomonitoring.
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Ficha de Projecto


Bolsa de Doutoramento FRCT

Understanding the respiratory effects of volcanogenic air pollution: a toxicogenomic approach

Bolseiro: Ricardo Camarinho
Entidade financiadora: FRCT
Contrato nº: M3.1.a/F/048/2015
Duração: 2016-2020

Data de Início

01-10-2016
Data de Encerramento

30-09-2020

Anexos


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